We synthesize and evaluate dynamic biopolymers for therapeutic applications. This includes nano- and microparticles for the delivery of siRNA, proteins and small molecule drugs. Combining chemistry with biology and medicine we are working on novel approaches to solve therapeutic obstacles for future strategies allowing true personalized medicinal applications.
Artificial nanostructures are very similar in size and shape to many biological species such as proteins or viruses. Nature’s toolbox provides us with a variety of biopolymers, such as polysaccharides, lipids, or proteins. Our research group applies a variety of bioorganic chemistry methods to produce functionalized nanomaterials in order to mimic biological properties, while maintaining biocompatibility and degradability.