Research Topics

Explore the scientific questions that fascinate us

PROJECTS OVERVIEW

 We synthesize and evaluate dynamic biopolymers for therapeutic applications. This includes nano- and microparticles for the delivery of siRNA, proteins and small molecule drugs. Combining chemistry with biology and medicine we are working on novel approaches to solve therapeutic obstacles for future strategies allowing true personalized medicinal applications.

 Artificial nanostructures are very similar in size and shape to many biological species such as proteins or viruses. Nature’s toolbox provides us with a variety of biopolymers, such as carbohydrates, lipids, or polypeptides. Our research group applies a variety of chemistry methods to produce functionalized nanomaterials in order to mimic biological properties, while maintaining biocompatibility and degradability.
nanometer scale comparison nanoparticle size comparison nanotechnology chart ruler

METHODS

Biopolymer Scaffolds

We modify natural biopolymers (sugars, peptides, proteins) to optimize their properties beyond the original functions.

Chemical Modification

The extensive toolkit of bioorganic chemistry provides various possibilites for chemical functionalization.

Nanoparticle Formation

We apply various biotechnological techniques to form micro- and nanoparticles in tunable sizes.

Biological Testing

Cellular functions and the bioactivity of the produced biomaterials are analyzed in-house with in vitro tests.

Summary Wichlab

“Stay Hungry – Stay Foolish”

Steve Jobs, C.E.O. Apple Computers

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