Journals/Books

Enzyme Bioink for the 3D Printing of Biocatalytic Materials Luca A Altevogt, Rakib H Sheikh, Thomas G Molley, Joel Yong, Kang Liang, Patrick Spicer, Kristopher A Kilian, Peter R Wich bioRxiv 2024.02.04.577699; doi: https://doi.org/10.1101/2024.02.04.577699“Enzyme Bioink for the 3D Printing of Biocatalytic Materials”
L. A. Altevogt, R. H. Sheikh, T. G. Molley, J. Yong, K. Liang, P. Spicer, K. A. Kilian, P. R. Wich
bioRxiv, 2024, 2024.02.04.577699. (DOI: https://doi.org/10.1101/2024.02.04.577699)

 

“Dual-Responsive Enzyme–Polysaccharide Conjugate as a Nanocarrier System for Enzyme Prodrug Therapy” M. Konhäuser, V. K. Kannaujiya, J. Kaltbeitzel, P. Winterwerber, E. Böhm, B. Breitenbach, P. R. Wich Biomacromolecules, 2023, accepted. (DOI: 10.1021/acs.biomac.3c00031)
“Dual-Responsive Enzyme–Polysaccharide Conjugate as a Nanocarrier System for Enzyme Prodrug Therapy”
M. Konhäuser, V. K. Kannaujiya, J. Kaltbeitzel, P. Winterwerber, E. Böhm, B. Breitenbach, P. R. Wich
Biomacromolecules, 2023, 24, 2138–2148. (DOI: 10.1021/acs.biomac.3c00031)

 

“Protein-based Nanoparticles: From Drug Delivery to Imaging, Nanocatalysis and Protein Therapy ” J. Kaltbeitzel, P. R. Wich Angew. Chem. 2023, e202216097. (DOI: 10.1002/anie.202216097)“Protein-based Nanoparticles: From Drug Delivery to Imaging, Nanocatalysis and Protein Therapy ”
J. Kaltbeitzel, P. R. Wich
Angew. Chem. Int. Ed. 2023, e202216097. (DOI: 10.1002/anie.202216097)

German Version:
“Protein‐basierte Nanopartikel: Von Wirkstofftransport zu Bildgebung, Nanokatalyse und Proteintherapie”
J. Kaltbeitzel, P. R. Wich
Angew. Chem. 2023, e202216097. (DOI: 10.1002/ange.202216097)

 

“Anticancer activity of NFκB decoy oligonucleotide-loaded nanoparticles against human lung cancer” V. K. Kannaujiya, G. De Rubis, K. R. Paudel, B. Manandhar, D. K. Chellappan, S. K. Singh, R. MacLoughlin, G. Gupta, D. Xenaki, P. Kumar, P. M. Hansbro, B. G. G. Oliver, P. R. Wich, K. Dua J. Drug Delivery Sci. Technol. 2023, 82, 104328. (DOI: 10.1016/j.jddst.2023.104328)“Anticancer activity of NFκB decoy oligonucleotide-loaded nanoparticles against human lung cancer”
V. K. Kannaujiya, G. De Rubis, K. R. Paudel, B. Manandhar, D. K. Chellappan, S. K. Singh, R. MacLoughlin, G. Gupta, D. Xenaki, P. Kumar, P. M. Hansbro, B. G. G. Oliver, P. R. Wich, K. Dua
J. Drug Delivery Sci. Technol. 2023, 82, 104328. (DOI: 10.1016/j.jddst.2023.104328)

 

Drug Delivery Systems for Metabolic Disorders“Drug Delivery Systems for Metabolic Disorders” (book)
H. Dureja, S. N. Murthy, P. R. Wich and K. Dua
Elsevier, 2022, ISBN: 978-0-323-99616-7
(comprehensive coverage of advanced drug delivery systems to treat metabolic diseases, including recent research on diagnostic methods and treatment strategies – 1st edition, 32 chapters, 505 pages)

 

Advances and applications of dextran-based nanomaterials targeting inflammatory respiratory diseases

“Advances and applications of dextran-based nanomaterials targeting inflammatory respiratory diseases”
P. Prasher, M. Sharma, S. K. Singh, M. Haghi, R. MacLoughlin, D.K. Chellappan, G. Gupta, K. R. Paudel, P. M. Hansbro, B.G.G. Oliver, P. R. Wich, K. Dua
J. Drug Delivery Sci. Technol., 2022, 74, 103598. (DOI: 10.1016/j.jddst.2022.103598)

 

“Versatility of acetalated dextran in nanocarriers targeting respiratory diseases”
P. Prasher, M. Sharma, S. K. Singh, M. Gulati, D. Kumar, G.Gupta, D.K. Chellappan, B. G.G. Oliver, P. R. Wich, K. Dua
Mater. Lett., 2022, 132600. (DOI: 10.1016/j.matlet.2022.132600)

 

 

 

“Co-Encapsulation of L-Asparaginase and Etoposide in Dextran Nanoparticles for Synergistic Effect in Chronic Myeloid Leukemia Cells”
M.Konhäuser, V. K. Kannaujiy, E. Steiert, K. Schwickert, T. Schirmeister, P. R. Wich
Int. J. Pharm., 2022, 121796. (DOI: 10.1016/j.ijpharm.2022.121796)

 

 

 

“Attenuation of Cigarette-Smoke-Induced Oxidative Stress, Senescence, and Inflammation by Berberine-Loaded Liquid Crystalline Nanoparticles: In Vitro Study in 16HBE and RAW264.7 Cells”
K. R. Paudel, N. Panth, B. Manandhar, S. K. Singh, G. Gupta, P. R. Wich, Srinivas Nammi, R. MacLoughlin, J. Adams, M. E. Warkiani, D. K. Chellappan 15 , B. G. Oliver, P. M. Hansbro, K. Dua
Antioxidants, 2022, 11, 873. (DOI: 10.3390/antiox11050873)

 

 

 

“Nanoparticulate strategies for the delivery of miRNA mimics and inhibitors in anticancer therapy and its potential utility in oral submucous fibrosis”
J. Manikkath, P. V. Jishnu, P. R. Wich, A. Manikkath, R. Radhakrishnan
Nanomedicine, 2022, 17 (3), 181–195. (DOI: 10.2217/nnm-2021-0381)

 

 

 

 

Can dextran-based nanoparticles mitigate inflammatory lung diseases

“Can dextran-based nanoparticles mitigate inflammatory lung diseases?”
P. Prasher, M. Sharma, P. R. Wich, N.K. Jha, S. K. Singh, D. K. Chellappan, K. Dua
Future Med Chem., 202113 (23), 2027–2031. (DOI: 10.4155/fmc-2021-0218)

 

 

 

 

Recent trends of NFκB decoy oligodeoxynucleotide-based nanotherapeutics in lung diseases“Recent trends of NFκB decoy oligodeoxynucleotide-based nanotherapeutics in lung diseases”
M. Mehta, K. R. Paudel, S. D. Shukla, V. S. R. R. Allam, V. K. Kannaujiya, N. Panth, A. Das, V. K. Parihar, A. Chakraborty, M. K. Ali, N. Ku. Jha, D. Xenaki, Q. P. Su, P. R. Wich, J. A., P. M. Hansbro, D. K. Chellappan, B. G. G. Oliver, K. Dua
J. Controlled Release, 2021, 337, 629–644. (DOI: 10.1016/j.jconrel.2021.08.010)

 

 

 

 

Treatment of chronic airway diseases using nutraceuticals: Mechanistic insight“Treatment of chronic airway diseases using nutraceuticals: Mechanistic insight”
V. S. R. R. Allam, D. K. Chellappan, N. K. Jha, M. D. Shastri, G. Gupta, S. D. Shukla, S. K. Singh, K. Sunkara, N. Chitranshi, V. Gupta, P. R. Wich, R. MacLoughlin, B. G. G. Oliver, S. Wernersson, G. Pejler, K. Dua
Crit. Rev. Food Sci. Nutr., 2021, 1-15. (DOI: 10.1080/10408398.2021.1915744)

 

 

 

“Targeting respiratory diseases using miRNA inhibitor based nanotherapeutics: Current status and future perspectives” M. Mehta, S. Satija, K. R. Paudel, V. Malyla, V. K. Kannaujiya, D. K. Chellappan, M. Bebawy, P. M. Hansbro, P. R. Wich, K. Dua, Nanomedicine: NBM, 2020, 102303.“Targeting respiratory diseases using miRNA inhibitor based nanotherapeutics: Current status and future perspectives”
M. Mehta, S. Satija, K. R. Paudel, V. Malyla, V. K. Kannaujiya, D. K. Chellappan, M. Bebawy, P. M. Hansbro, P. R. Wich, K. Dua
Nanomedicine: NBM, 2021, 31, 102303. (DOI: 10.1016/j.nano.2020.102303)

 

 

"Metal-organic frameworks as protective matrices for peptide therapeutics” J. Liu, Z. Guo, M. Kordanovski, J. Kaltbeitzel, H. Zhang, Z. Cao, Z. Gu, P. Wich, M. Lord, K. Liang, J. Colloid Interface Sci., 2020, 576, 356–363.“Metal-organic frameworks as protective matrices for peptide therapeutics”
J. Liu, Z. Guo, M. Kordanovski, J. Kaltbeitzel, H. Zhang, Z. Cao, Z. Gu, P. Wich, M. Lord, K. Liang
J. Colloid Interface Sci., 2020, 576, 356–363. (DOI: 10.1016/j.jcis.2020.05.057)

 

 

 

Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and Immunological Perspective” P. Prasher, M. Sharma, M. Mehta, S. Satija, K. R. Paudel, D. K. Chellappan, H. Dureja, G. Gupta, M. M. Tambuwala, P. Negi, P. R. Wich, N. Hansbro, P. M Hansbro, K. Dua, Chem.-Biol. Interact., 2020

“Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and Immunological Perspective”
P. Prasher, M. Sharma, M. Mehta, S. Satija, K. R. Paudel, D. K. Chellappan, H. Dureja, G. Gupta, M. M. Tambuwala, P. Negi, P. R. Wich, N. Hansbro, P. M Hansbro, K. Dua
Chem.-Biol. Interact., 2020325, 109125. (DOI: 10.1016/j.cbi.2020.109125)

 

 

Detailed algal extracellular carbohydrate-protein characterisation lends insight into algal solid-liquid separation process outcomes

“Detailed algal extracellular carbohydrate-protein characterisation lends insight into algal solid-liquid separation process outcomes”
N. R. H. Rao, A. M. Granville, P. R. Wich, R. K. Henderson
Water Res., 2020178, 115833(DOI: 10.1016/j.watres.2020.115833)

 

 

 

miRNA nanotherapeutics: Potential and challenges in respiratory disorders” M. Mehta, D.K. Chellappan, P. R. Wich, N. G. Hansbro, P. M. Hansbro, K. P. Dua Future Med. Chem., 2020

“miRNA nanotherapeutics: Potential and challenges in respiratory disorders”
M. Mehta, D.K. Chellappan, P. R. Wich, N. G. Hansbro, P. M. Hansbro, K. P. Dua
Future Med. Chem., 202012(11), 987-990. (DOI: 10.4155/fmc-2020-0066)

 

 

 

Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: An update

“Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update.”
M. Mehta, D. S. Dhanjal, K. R. Paudel, B. Singh, G. Gupta, R. S, L. Thangavelu, M. M. Tambuwala5, H. A. Bakshi, D. K. Chellappan, P. Pandey, H. Dureja, N. B. Charbe, S. K. Singh, S. D. Shukla, S. Nammi, P. R. Wich, P. M. Hansbro, S. Satija, K. Dua
Inflammopharmacol., 202028, 795–817. (DOI: 10.1007/s10787-020-00698-3)

 

 

 

Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A

“Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A”
F. Barthels, G. Marincola, T. Marciniak, M. Konhäuser, S. Hammerschmidt, J. Bierlmeier, U. Distler, P. R. Wich, S. Tenzer, D. Schwarzer, W. Ziebuhr, T. Schirmeister
ChemMedChem, 202015, 839–850. (DOI: 10.1002/cmdc.201900687)

 

 

 

pH-Responsive protein nanoparticles via conjugation of degradable PEG to the surface of cytochrome c

“pH-Responsive Protein Nanoparticles via Conjugation of Degradable PEG to the Surface of Cytochrome c
E. Steiert, J. Ewald, A. Wagner, U. A. Hellmich, H. Frey and P. R. Wich
Polym. Chem., 2020, 11, 551 – 559. (DOI: 10.1039/C9PY01162E)
(Special collection: Polymer Chemistry Emerging Investigators 2020)

 

 

 

Receptor-mediated Uptake of Folic Acid-functionalized Dextran Nanoparticles for Applications in Photodynamic Therapy

“Receptor-mediated Uptake of Folic Acid-functionalized Dextran Nanoparticles for Applications in Photodynamic Therapy” K. Butzbach, M. Konhäuser, D. N. Bamberger, B. Breitenbach, B. Epe and P. R. Wich
Polymers, 2019, 11, 896. (DOI: 10.3390/polym11050896)

 

 

 

Xylochemical Synthesis of Cytotoxic 2-Aminophenoxazinone-Type Natural Products Through Oxidative Cross Coupling” J. Kühlborn, M. Konhäuser, J. Groß, P. R. Wich, and Till Opatz, ACS Sustainable Chem. Eng., 2019

“Xylochemical Synthesis of Cytotoxic 2-Aminophenoxazinone-Type Natural Products Through Oxidative Cross Coupling”
J. Kühlborn, M. Konhäuser, J. Groß, P. R. Wich, and Till Opatz
ACS Sustainable Chem. Eng, 2019, 7(4), 4414–4419 (DOI: 10.1021/acssuschemeng.8b06353)

 

 

 

Soft Matter Double Responsive Dextran Micelles Micellar Nanoparticle Benjamin Breitenbach Peter Wich

“Double Stimuli-Responsive Polysaccharide Block Copolymers as Green Macrosurfactant for Near-Infrared Photodynamic Therapy”
B. Breitenbach, E. Steiert, M. Konhäuser, L.-M.Vogt, Y. Wang, S. H. Parekh and P. R. Wich
Soft Matter, 2019, 15, 1423–1434. (DOI: 10.1039/C8SM02204F)
(Special Edition: Soft Matter Emerging Investigators 2019)

 

 

 

Delivering all in one: Antigen-nanocapsule loaded with dual adjuvant yields superadditive effects by DC-directed T cell stimulation“Delivering all in one: Antigen-nanocapsule loaded with dual adjuvant yields superadditive effects by DC-directed T cell stimulation”
D. Paßlick, K. Piradashvili, D. Bamberger, M. Li, S. Jiang, D. Strand, P. R. Wich, K. Landfester, S. Grabbe, M. Bros, V. Mailänder
J. Controlled Release. 2018, 289, 23–34.(DOI: 10.1016/j.jconrel.2018.09.008)

 

 

 

Protein‐Based Nanoparticles for the Delivery of Enzymes with Antibacterial Activity“Protein‐Based Nanoparticles for the Delivery of Enzymes with Antibacterial Activity”
E. Steiert, L. Radi, M. Fach, P. R. Wich
Macromol. Rapid Commun. 201839,1800186 (DOI: 10.1002/marc.201800186)

 

 

 

Dextran Nanoparticles Immune cell stimulation PEGylation DEXylation“Surface Modification of Polysaccharide-Based Nanoparticles with PEG and Dextran and their Effects on Immune Cell Binding and Stimulatory Characteristics”
D. Bamberger, D. Hobernik, Matthias Konhäuser, M. Bros, P. R. Wich
Mol. Pharmaceutics 2017, 14 (12), 4403–4416 (DOI: acs.molpharmaceut.7b00507)

 

 

 

Wichlab Peter Wich Journal of Medicinal Chemistry“Development of Novel Peptide-based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs)”
S. Previti, R. Ettari, S. Cosconati, G. Amendola, K. Chouchene, A. Wagner, U. A. Hellmich, K. Ulrich, R. L. Krauth-Siegel, I. Schmid, P. R. Wich, T. Schirmeister, J. Gut, P. J. Rosenthal, S. Grasso, M. Zappalà
J. Med. Chem. 2017, 60 (16), 6911–6923. (DOI: 10.1021/acs.jmedchem.7b00405)

 

 

 

Biomacromolecules Dextran Micelles Nanoparticle Benjamin Breitenbach Ira Schmid Peter Wich

“Amphiphilic Polysaccharide Block Copolymers for pH-responsive Micellar Nanoparticles”
B. Breitenbach, I. Schmid, P. R. Wich
Biomacromolecules 2017, 18 (9), 2839–2848. (DOI: 10.1021/acs.biomac.7b00771)

 

 

 

Nanomedicine Bamberger Wich Wichlab Dextran Nanoparticles“Dextran-based Therapeutic Nanoparticles for Hepatic Drug Delivery”
F. Foerster, D. Bamberger, J. Schupp, M. Weilbächer, L. Kaps, S. Strobl, L. Radi, M. Diken, D. Strand, A. Tuettenberg, P. R. Wich, D. Schuppan
Nanomedicine 2016, 11 (20), 2663–2677. (DOI: 10.2217/nnm-2016-0156)

 

 

 

MedChemComm Radi Fach Wich

“Methods of Protein Surface PEGylation under Structure Preservation for the Emulsion-based Formation of Stable Nanoparticles”
L. Radi, M. Fach, M. Montigny, E. Berger-Nicoletti, W. Tremel, P. R. Wich
Med. Chem. Commun. 2016, 7, 1738–1744 (DOI: 10.1039/C5MD00475F)
(This article is part of themed collection: New Talent: Europe)

 

 

“Nanoparticle Assembly of Surface-Modified Proteins” JACS Wich Fach Radi
M. Fach, L. Radi, P. R. Wich
J. Am. Chem. Soc., 2016, 138 (45), 14820–14823 (DOI: 10.1021/jacs.6b06243)

 

 

 

“Quantum Chemical-Based Protocol for the Rational Design of Covalent Inhibitors”JACS Schirmeister Engels Wich
T. Schirmeister, J. Kesselring, S. Jung, T. H. Schneider, A. Weickert, J. Becker, W. Lee, D. Bamberger, P. R. Wich, U. Distler, S. Tenzer, P. Johé, U. A. Hellmich, B. Engels
J. Am. Chem. Soc., 2016, 138 (27), 8332–8335. (DOI: 10.1021/jacs.6b03052)

 

 

 

“Organische Chemie – Beyer/Walter”2016 Beyer Walter - Organische Chemie Lehrbuch - Schirmeister Schmuck Wich T. Schirmeister, C. Schmuck, P. R. Wich
S. Hirzel Verlag 2016. (read more in our blog post) (Announcement: Ein Klassiker feiert Jubiläum)
(fundamentally revised edition – restructuring includes 38 chapters, complete coverage of all fields of organic chemistry; content update and revision of all structural formulas and diagrams; 1176 pages, 25th edition)

 

 

 

“Biopolymere – Baukasten der Natur” Biopolymere - Biopolymers Wichlab
P. R. Wich
Nachrichten aus der Chemie, 2015, 63 (2), 128–138. (DOI: 10.1002/nadc.201590046) (pdf download)

 

 

 

publications-2013-Jiang-OrgBiomolChem
“A New Approach to Inhibit Human β-Tryptase by Protein Surface Binding of Four-Armed Peptide Ligands with Two Different Sets of Arms”
Q.-Q. Jiang, L. Bartsch, W. Sicking, P. R. Wich, D. Heider,D. Hoffmann, C. Schmuck
Org. Biomol. Chem. 201311, 1631–1639. (DOI: 10.1039/C3OB27302D). (selected as Organic & Biomolecular Chemistry HOT Article)

 

 

publications-17“Aerosolized Antimicrobial Agents Based on Degradable Dextran Nanoparticles Loaded with Silver Carbene Complexes”
C. Ornelas-Megiatto, P. Shah, P.R. Wich, J. Cohen, J. Tagaev, J. Smolen, B. Wright, M. Panzner, W. Youngs, J. M. J. Fréchet, C. Cannon
Mol. Pharmaceutics. 2012, 9 (11), 3012–3022. (DOI: 10.1021/mp3004379)

 

 

 

publications-16“Conjugation Chemistry through Acetals toward a Dextran-Based Delivery System for Controlled Release of siRNA”
L. Cui, J. L. Cohen, C. K. Chu, P. R. Wich, P. H. Kierstead, J. M. J. Fréchet
J. Am. Chem. Soc. 2012134 (38), 15840–15848. (DOI: 10.1021/ja305552u)

 

 

 

publications-15“Polyphosphonium Polymers for siRNA Delivery: An Efficient and Non-Toxic Alternative to Polyammonium Carriers”
C. Ornelas-Megiatto, P. R. Wich, J. M. J. Fréchet
J. Am. Chem. Soc. 2012134, 1902–1905. (DOI: 10.1021/ja207366k)

 

 

 

publications-14“Degradable Dextran Particles for Gene Delivery Applications”
P. R. Wich, J. M. J. Fréchet
Aust. J. Chem. 20121, 15-19. (DOI: 10.1071/CH11370)

 

 

 

Surface Recognition and Inhibition of β-Tryptase by Tetravalent Peptide Ligands“Surface Recognition and Inhibition of β-Tryptase by Tetravalent Peptide Ligands”
P. R. Wich, C. Schmuck
Peptide Science 2010: Proceedings of the Fifth International Peptide Symposium, Kyoto, Japan, 04.-09. Dec 2010, (Ed.: N. Fujii, Y. Kiso), The Japanese Peptide Society,2011, p 59.

 

 

publications-12“Acid-Degradable Cationic Dextran Particles for the Delivery of siRNA Therapeutics”
J. L. Cohen, S. Schubert, P. R. Wich, L. Cui, J. A. Cohen, J. L. Mynar, and J. M. J. Fréchet
Bioconj. Chem. 201122, 1056–1065. (DOI: 10.1021/bc100542r)

 

 

 

publications-11“Reversible and Non-Competitive Inhibition of β-Tryptase by Tetravalent Peptide Ligands Identified from a Combinatorial Split-Mix-Library”
P. R. Wich, C. Schmuck
Angew. Chem. Int. Ed. 201049, 4113–4116. (DOI: 10.1002/anie.200907221)

 

 

publications-10“Site-specific pKa determination of the carboxylate-binding subunit in artificial peptide receptors”
S. Niebling, S. K. Srivastava, C. Herrmann, P. R. Wich, C. Schmuck, S. Schlücke
Chem. Commun. 201046, 2133–2135. (DOI: 10.1039/B926514G)

 

 

 

publications-09“Characterization of guanidiniocarbonyl pyrroles in water by pH-dependent UV Raman spectroscopy and component analysis”
S. K. Srivastava, S. Niebling, B. Küstner, P. R. Wich, C. Schmuck, S. Schlücker
Phys. Chem. Chem. Phys. 200810, 6770–6775. (DOI: 10.1039/b810908g)

 

 

 

publications-08“A Facile and Efficient Multi-Gram Synthesis of N-Protected 5-(Guanidinocarbonyl)-1H-pyrrole-2-carboxylic Acids”
C. Schmuck, V. Bickert, M. Merschky, L. Geiger, D. Rupprecht, J. Dudaczek, P. Wich, T. Rehm, U. Machon
Eur. J. Org. Chem. 20082, 324–329. (DOI: 10.1002/ejoc.200700756)

 

 

publications-07“UV resonance Raman spectroscopic monitoring of supramolecular complex formation: peptide recognition in aqueous solution”
B. Küstner, C. Schmuck, P. Wich, C. Jehn, S. K. Srivastava, S. Schlücker
Phys. Chem. Chem. Phys. 2007,32, 4598–4603. (DOI: 10.1039/b709142g)

 

 

 

publications-06“The Development of Artificial Receptors for Small Peptides Using Combinatorial Approaches”
C. Schmuck, P. Wich
Topics Curr. Chem. 2007277, 3–30. (Creative Chemical Sensor Systems, Volume Editor, Th. Schrader) (DOI: 10.1007/128_2007_111)

 

 

 

publications-05“Direct and Label-Free Detection of Solid-Phase-Bound Compounds by Using Surface-Enhanced Raman Scattering Microspectroscopy”
C. Schmuck, P. Wich, B. Küstner, W. Kiefer and S. Schlücker
Angew. Chem. Int. Ed. 200746, 4786–4789. (DOI: 10.1002/anie.200605190)

 

 

 

publications-04“Atropodiastereoselective Cleavage of Configurationally Unstable Biaryl Lactones with Amino Acid Esters”
G. Bringmann, H. Scharl, K. Maksimenka, K. Radacki, H. Braunschweig, P. Wich, C. Schmuck
Eur. J. Org. Chem. 2006, 4349–4361. (DOI: 10.1002/ejoc.200600311)

 

 

 

publications-03“Combinatorial receptor finding – small and focused vs. large and random libraries”
C. Schmuck, P. Wich
New J. Chem.200630, 1377–1385. (DOI: 10.1039/b605731b)

 

 

 

publications-02“Sequence-Dependent Stereoselectivity in the Binding of Tetrapeptides in Water by a Flexible Artificial Receptor”
C. Schmuck, P. Wich
Angew. Chem. Int. Ed. 200645, 4277–4281. (DOI: 10.1002/anie.200601046)  (Angew. Chem. 2006, 118, 4383–4387. DOI: 10.1002/ange.200601046)

 

 

“Synthesis and Reactivity of an Enantiomerically Pure N-Methyl-2-silyl Substituted Pyrrolidine”
K. Strohfeldt, T. Seibel, P. Wich, C. Strohmann
Organosilicon Chemistry VI, (Hrsg.: N. Auner, J. Weis), Wiley-VCH, Weinheim, 2005. (DOI: 10.1002/9783527618224) (Publisher Link)

Oral Presentations

55. David Sangster Award Plenary Talk, 17th Pacific Polymer Conference, Brisbane, Australia, 16. Dec 2022. (Plenary)

54. 17th Pacific Polymer Conference, Brisbane, Australia, 16. Dec 2022. (invited)

53. Monash University, Material Science & Engineering Seminar, Melbourne, Australia, 13. Oct 2022. (invited)

52. 12th International Nanomedicine Conference, Sydney, Australia, 28. Jun 2022. (invited)

51. 4th G‘L’owing Polymer Symposium (Kanto Branch, Society of Polymer Science, Japan), Online Symposium, 31. Jul 2021. (invited)

50. Australasian Polymer Summer School (APSS), ANU Canberra, Australia, 20. Jan 2020. (invited)

49. Drug Delivery Australia Conference (CRS 2019), Brisbane, Australia, 18. Nov 2019.

48. 37th Australasian Polymer Symposium APS, Sunshine Coast, Australia, 10. Nov 2019.

47. Centre for Advanced Food Enginomics (CAFE) Seminar, The University of Sydney, Sydney, Australia, 01. Nov 2019. (invited)

46. Chemeca 2019, SMC Conference and Function Centre, Sydney, Australia, 29. Sep 2019. 

45. UNSW Chemistry Seminar, UNSW, Sydney, Australia, 05. Sep 2019. (invited)

44. Biomimetics in Bioengineering 2019, Nature Conferences, QUT, Brisbane, Australia, 04. Aug 2019. (invited)

43. Sydney Surfaces And Soft Stuff Meeting 2019, UNSW, Sydney, Australia, 30. May 2019.

42. Manufacturing with Advanced Materials Seminar Series, Soft Matter Materials Laboratory, QUT, Brisbane, Australia, 10. Jan 2019. (invited)

41. Adult Cancer Program (ACP) Seminar, Lowy Cancer Research Centre, Sydney, Australia, 25. Oct 2018. (invited)

40. “Biopolymer-based Nanoparticles for Applications in Drug Delivery and Immunotherapy” P. R. Wich, World Polymer Congress MACRO18, Cairns, Australia, 5. Jul 2018.

39. “Full Polysaccharide Amphiphilic Block Copolymers for Nanoparticulate Drug Delivery” P. R. Wich, World Polymer Congress MACRO18, Cairns, Australia, 3. Jul 2018.

38. “Protein-based Nanoparticles: A New Class of Multifunctional Biomaterials” P. R. Wich, World Polymer Congress MACRO18, Cairns, Australia, 2. Jul 2018.

37. “Biopolymer-based Nanoparticles for Applications in Drug Delivery and Immunotherapy” P. R. Wich, 9th International Nanomedicine Conference, Coogee, Australia, 25. Jun 2018. (invited)

36. “Polysaccharides and Proteins as Versatile Biopolymer Material for Nanoparticles” P. R. Wich, Sino-German Young Researcher Workshop, LMU Munich, Germany, 6. Apr 2018. (invited)

35. “Biopolymer-based Nanoparticles for Applications in Drug Delivery and Immunotherapy” P. R. Wich, Department Seminar, Helmholtz Institute for Pharmaceutical Research Saarland, Saarbrücken, Germany, 30. Jan 2018. (invited)

34. “Biopolymer-based Nanoparticles for Applications in Drug Delivery and Immunotherapy” P. R. Wich, Department Seminar, Technische Universität Wien, Austria, 6. Nov 2017. (invited)

33. “Biopolymer-based Nanoparticles for Applications in Drug Delivery and Immunotherapy” P. R. Wich, Nachwuchswissenschaftler-Workshop, GDCh Makro. Chemie, Ludwigshafen, Germany, 25. Sep 2017.

32. “Protein-based Nanoparticles: A New Class of Multifunctional Biomaterials” P. R. Wich, Bayreuth Polymer Symposium 2017, Bayreuth, Germany, 17-19. Sep 2017.

31. “Amphiphilic Polysaccharide Block Copolymers for Nanoparticulate Drug Delivery ” P. R. Wich, ACS 254th National Meeting & Exposition, Washington D.C., USA, 20.-24. Aug 2017. (invited)

30. “Biopolymer-based nanoparticles for applications in drug delivery and immunotherapy” P. R. Wich, ACS 254th National Meeting & Exposition, Washington D.C., USA, 20.-24. Aug 2017.

29. “Protein-based nanoparticles: A new class of multifunctional biomaterials” P. R. Wich, ACS 254th National Meeting & Exposition, Washington D.C., USA, 20.-24. Aug 2017.

28. “Biopolymer-based Nanoparticles for Applications in Drug Delivery and Immunotherapy” P. R. Wich, Department Seminar, University Jena, Jena Center for Soft Matter (JCSM), Germany, 13. Jul 2017. (invited)

27. “Nanoparticle Assembly of Surface-modified Proteins” P. R. Wich, ACS 253th National Meeting & Exposition, San Francisco, USA, 02.-06. Apr 2017.

26. “Surface-modified Proteins as New Type of Biomaterials for Nanoparticles” P. R. Wich, Chemiedozententagung 2017, Marburg, Germany, 13.-15. Feb 2017.

25. “Biopolymers as Multifunctional Materials for Nanoparticulate Drug Delivery” P. R. Wich, DPhG-Jahrestagung 2016, München, Germany, 05.-07. Oct 2016.

24. “Biopolymer-based Nanoparticles: Dynamic Materials for Drug Delivery” P. R. Wich, Warwick Polymer Conference 2016, Warwick, UK, 11.–14. Jul 2016.

23. “Biopolymer-based Nanoparticles: Dynamic Materials for Drug Delivery” P. R. Wich, Global Forum on Advanced Materials and Technologies for Sustainable Development (GFMAT 2016), Toronto, Canada, 26. Jun – 01. Jul 2016.

22. “Protein-based Nanoparticles by Lipophilic Surface Modification of Lysozyme” P. R. Wich, Chemiedozententagung, Heidelberg, Germany, 21.–23. Mar 2016.

21. “Biopolymers as Dynamic Materials for Nanoparticulate Drug Delivery” P. R. Wich, 24. Nachwuchswissenschaftler-Symposium Bioorganische Chemie, Hamburg, Germany, 23.–25. Sep 2015.

20. “Acid-Degradable Polysaccharide Nanoparticles for the Delivery of Biotherapeutics” P. R. Wich, 6th European Conference Chemistry in the Life Sciences (ECCLS), Lisbon, Portugal, 12. Jun 2015.

19. “Biopolymers as Versatile Materials for Molecular Recognition and Drug Delivery” P. R. Wich, TU Braunschweig, GDCh Colloqium, Braunschweig, Germany, 08. Jun 2015.

18. “Supramolecular and Nanoparticulate Biopolymers for Therapeutic Applications” P. R. Wich, Lehrstuhl für Funktionswerkstoffe FMZ-LCTM Institutskolloqium, Würzburg, Germany, 06. May 2015.

17. “Biopolymers for Supramolecular Recognition and Nanoparticulate Drug Delivery” P. R. Wich, Frauenhofer ICT-IMM Institutskolloquium, Mainz, Germany, 13. Nov 2014.

16. “Supramolecular Recognition of Peptides and Proteins – An Attractive Tale” P. R. Wich, Reaxys Inspiring Chemistry Conference 2014, Grindelwald, Switzerland, 21.–24. Sep 2014.

15. “Dynamic Polysaccharide-based Carrier Systems for the Delivery of Biotherapeutics” P. R. Wich, 26th European Conference on Biomaterials, Liverpool, UK,  31. Aug. – 3. Sep 2014.

14. “Playing with Nature’s Toolkit” P. R. Wich, From Graduation to Innovation (GDCh/REAXYS event), Chemnitz, Germany, 24. Jun 2014.

13. “Supramolecular and Nanoparticulate Biopolymers for Therapeutic Applications” P. R. Wich, Frontiers in Medicinal Chemistry, Tübingen, Germany, 19. Mar 2014.

12. “Multifunctional Polysaccharide Nanoparticles with Tunable Degradability” P. R. Wich, SFB 1066 Seminar, Mainz, Germany, 27. Jan 2014.

11. “ Polymeric Particles as Multifunctional Delivery Systems for Biotherapeutics” P. R. Wich, Reaxys Inspiring Chemistry Conference 2013, Grindelwald, Switzerland, 22.–24. Sep 2013.

10. “Breaking the Walls of Protein Manipulation” P. R. Wich, Falling Walls Lab, Berlin, Germany, 8. Nov 2012.

9. “Acid-Degradable Dextran Particles for the Delivery of Biotherapeutics” P. R. Wich, DPhG-Jahrestagung 2012, Greifswald, Germany, 11.–13. Oct 2012.

8. “Dextran Based Particle Systems as Multifunctional Delivery Vehicles” P. R. Wich, J. M. J. Fréchet, 2nd International NanoMedicine Conference, Sydney, Australia,14.-16. Jul 2011.

7. “Surface Recognition and Inhibition of β-Tryptase by Tetravalent Peptide Ligands” P. R. Wich, C. Schmuck, 5th International Peptide Symposium, Kyoto, Japan, 04.-09. Dec 2010.

6. “Polymeric Particle Systems for the Delivery of Biotherapeutics” (invited plenary talk) P. R. Wich, J. M. J. Fréchet, ZING Polymer Chemistry Conference, Puerto Morelos, Mexico, 19.-22. Nov 2010.

5. “Acetal-modified Dextran Particles for siRNA Delivery” P. R. Wich, J. L. Cohen, S. Hornig, J. A. Cohen, J. M. J. Fréchet, 3rd EuCheMS Chemistry Congress, Nürnberg, Germany, 29. Aug – 02. Sep 2010.

4. “Artificial Oligopeptides as a Versatile Toolkit for Molecular Recognition Events – New Insights into Multivalency Effects, Protein Recognition and Enzyme Inhibition” P. R. Wich, oral presentation, 11th JCF-Frühjahrssymposium (JCF Spring Symposium), Essen, Germany, 11.-14. Mar 2009.

3. “Molecular recognition by one-armed artificial receptors in water – New insights from combinatorial methods as an ideal tool to identify peptide binders” P. Wich, oral presentation, Second Joint Ph.D. Students Meeting SFB 544/630, New Trends in Infectious Disease Research, Heidelberg, Germany, 23.-25. Nov 2006.

2. “Small and focused combinatorial libraries as a perfect tool to identify peptide binders” P. Wich, oral presentation, Intensive Course Medicinal Chemistry 2006, HoChiMinh-City, Vietnam, 02. Nov 2006.

1. “Combinatorial libraries as a tool to identify peptide binders: New insights into substrate- and sequence-selectivity” P. Wich, oral presentation, SFB 630-Colloquium, Würzburg, Germany, 17. Jul 2005.

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